A to Z Drug Facts

Acetaminophen (N-Acetyl-p-Aminophenol; APAP) (ass-cet-ah-MEE-noe-fen) Trade Name(s): Acephen Suppositories 120 mg Suppositories 325 mg Suppositories 650 mg Aceta Tablets 325 mg Tablets 500 mg Elixir 120 mg/5 mL Acetaminophen Uniserts Suppositories 120 mg Suppositories 325 mg Suppositories 650 mg Apacet Tablets, chewable 80 mg Solution 100 mg/mL Aspirin Free Anacin Maximum Strength Tablets 500 mg Caplets 500 mg Gelcaps 500 mg Aspirin Free Pain Relief Tablets 325 mg Tablets 500 mg Caplets 500 mg Children's Dynafed Jr. Tablets, chewable 80 mg Children's Feverall Suppositories 120 mg Tablets, chewable 120 mg Capsules, sprinkle 80 mg Children's Genapap Tablets, chewable 80 mg Elixir 160 mg/5 mL Children's Halenol Liquid 160 mg/5 mL Children's Mapap Tablets, chewable 80 mg Elixir 160 mg/5 mL Children's Pain Reliever Elixir 160 mg/5 mL Suspension 160 mg/5 mL Children's Panadol Tablets, chewable 80 mg Liquid 160 mg/5 mL Children's Silapap Elixir 80 mg/2.5 mL Children's Tylenol Tablets, chewable 80 mg Elixir 160 mg/5 mL Children's Tylenol Soft Chews Tablets, chewable 80 mg Dapacin Capsules 325 mg Extra Strength Dynafed E.X. Tablets 500 mg Feverall, Junior Strength Suppositories 325 mg Capsules, sprinkle 160 mg Feverall, Infants Suppositories 80 mg Genapap Tablets 325 mg Genapap, Infants' Drops Solution 100 mg/mL Genapap Extra Strength Tablets 500 mg Caplets 500 mg Genebs Tablets 325 mg Genebs Extra Strength Tablets 500 mg Caplets 500 mg Infants' Pain Reliever Drops 80 mg/0.8 mL Infants' Silapap Solution 100 mg/mL Junior Strength Panadol Caplets 160 mg Liquiprin Drops for Children Solution 80 mg/1.66 mL Mapap Extra Strength Tablets 500 mg Mapap Infant Drops Solution 100 mg/mL Mapap Regular Strength Tablets 325 mg Maranox Tablets 325 mg Meda Cap Capsules 500 mg Meda Tab Tablets 325 mg Neopap Suppositories 125 mg Oraphen-PD Elixir 120 mg/5 mL Panadol Tablets 500 mg Caplets 500 mg Panadol, Infants' Drops Solution 100 mg/mL Redutemp Tablets 500 mg Ridenol Elixir 80 mg/5 mL Tapanol Extra Strength Tablets 500 mg Caplets 500 mg Gelcaps 500 mg Tapanol Regular Strength Tablets 325 mg Tempra Tablets 160 mg Tempra 1 Solution 100 mg/mL Tempra 2 Syrup Liquid 160 mg/5 mL Tempra 3 Tablets, chewable 80 mg Tylenol Arthritis Tablets, extended-release 650 mg Tylenol Caplets Tablets 325 mg Tylenol Extended Relief Caplets 650 mg Tylenol Extra Strength Tablets 500 mg Gelcaps 500 mg Liquid 500 mg/15 mL Tylenol Infants' Drops Solution 100 mg/mL Tylenol Junior Strength Tablets 160 mg Tylenol Regular Strength Tablets 325 mg Uni-Ace Solution 100 mg/mL Abenol A.F. Anacin Apo-Acetaminophen Atasol Children's Acetaminophen Children's Chewable Acetaminophen Extra Strength Acetaminophen Pediatrix PMS-Acetaminophen Regular Strength Acetaminophen Tempra 222AF Tylenol Indicates Canadian Trade Name. Class: Analgesic Antipyretic Action: Inhibits prostaglandins in CNS but lacks anti-inflammatory effects in periphery; reduces fever through direct action on hypothalamic heat-regulating center. Indications: Relief of mild-to-moderate pain; treatment of fever. Contraindications: Standard considerations. Route/Dosage: Interactions: Ethanol: Chronic excessive use may increase risk of hepatotoxicity. Hydantoins, sulfinpyrazone: May decrease therapeutic effect of APAP; concomitant long-term use may increase risk of hepatotoxicity. Lab Test Interferences: With Chemstrip bG , Dextrostix , Visidex II home blood glucose measurement systems, drug may cause > 20% decrease in mean glucose. Adverse Reactions: hematologic: Hemolytic anemia; neutropenia; leukopenia; pancytopenia; thrombocytopenia. hepatic: Jaundice. other: Hypoglycemia; allergic skin eruptions or fever. Precautions: Pregnancy: Category B. Lactation: Excreted in breast milk. Hepatic impairment: Chronic alcoholics should not exceed 2 g/day. Persistent pain or fever: May indicate serious illness. Consult health care provider. Administration/Storage: Administer with water 30 min before or 2 hr after meals. Store tablets and capsules at room temperature in tightly closed container. Refrigerate suppositories. Refrigeration of elixir improves palatability. Assessment/Interventions: Obtain patient history, including drug history and any known allergies. Assess for pain and fever before and 1 to 2 hr after administration. Assess serum glucose and liver enzyme levels before long-term therapy. Patient/Family Education: Instruct family to consult health care provider for use in children < 3 yr and, not to continue taking drug > 5 days unless advised by health care provider. Instruct adult patients not to continue taking drug > 10 days for pain or 3 days for fever. Instruct patient/family to contact health care provider if pain or fever (> 103°F) persists > 3 days. Advise diabetic patients to use sugar-free form of drug.